Pa Disembala 2, 2021, BD (kampani ya bidi) idalengeza kuti yapeza kampani ya venclose. Wothandizira yankho amagwiritsidwa ntchito pochiza matenda osachiritsika a venous insufficiency (CVI), matenda omwe amayamba chifukwa cha kulephera kwa valve, komwe kungayambitse mitsempha ya varicose.
Radiofrequency ablation ndiye chithandizo chachikulu cha CVI ndipo amavomerezedwa kwambiri ndi madokotala. Poyerekeza ndi njira ina yothandizira laser ya CVI, kutulutsa catheter kwa radiofrequency kumatha kuchepetsa ululu wapambuyo pa opaleshoni ndi mikwingwirima. Vinclose ndi mtsogoleri pazamankhwala a CVI. Pulatifomu yake yaukadaulo yama radio frequency (RF) ablation ikufuna kukwaniritsa kusinthasintha, kuchita bwino komanso kuphweka.
Mzere wowonjezera wochotsa mitsempha
CVI ikuyimira kufunikira kokulirapo kwa chithandizo chamankhwala mkati mwadongosolo lazaumoyo - kukhudza 40% ya amayi ndi 17% ya amuna ku United States. Vinclose ndi mtsogoleri pazamankhwala a CVI. Pulatifomu yake yaukadaulo yama radio frequency (RF) ablation ikufuna kukwaniritsa kusinthasintha, kuchita bwino komanso kuphweka. Radiofrequency ablation ndiye chithandizo chachikulu cha CVI ndipo amavomerezedwa kwambiri ndi madokotala. Poyerekeza ndi njira ina yochizira laser ya CVI, kuchotsedwa kwa catheter ya radiofrequency kumatha kuchepetsa ululu wapambuyo pa opaleshoni ndi mikwingwirima.
"Tadzipereka kukhazikitsa mulingo watsopano wabwino kwambiri kwa odwala omwe ali ndi matenda a venous, omwe amayenera kupereka umisiri waluso kwa madokotala," atero paddy O'Brien, Purezidenti wapadziko lonse wa BD intervention. "Kupeza kwathu kwa venclose kudzatithandiza kupereka mayankho amphamvu kwambiri kwa madokotala omwe amachiza matenda osiyanasiyana a venous." Venclose ™ The radiofrequency ablation system imakwaniritsa bwino luso lathu lotsogola laukadaulo wamatenda a venous ndipo imagwirizana ndi cholinga chathu chopanga zatsopano komanso perekani njira zosinthira zochiritsira matenda osachiritsika ndikupangitsa kuti kusinthaku kukhale kotheka.
Venclose ™ Mapangidwe ophatikizika a makinawa amapereka kukula kwake kotentha (2.5 cm ndi 10 cm) mu catheter ya 6 Fr size. Catheter yotenthetsera iwiriyi imapatsa madokotala maubwino osiyanasiyana opangira.
Venclose ™ Kutentha kwa dongosololi ndi 30% yayitali kuposa ya katheta yayitali kwambiri yothamangitsa ma radiofrequency ablation, zomwe zimathandiza madotolo kutulutsa bwino mitsempha yambiri pakuwotcha kulikonse ndikuthandizira kuchepetsa kuchuluka kwa ma ablation omwe amafunikira pakuchiritsa kwa mtsempha. Kutentha kwapawiri kumatanthawuza kuti madotolo amatha kugwiritsa ntchito catheter yomweyi kuti awononge zigawo zazitali komanso zazifupi za venous - kuchepetsa kulemetsa kwa kasamalidwe ka zinthu poyerekeza ndi ma catheter okhala ndi zazifupi komanso / kapena static kutentha kwautali.
Ukadaulo wa dongosololi umapangidwanso kuti uthandizire kupereka njira yoyang'anira odwala. Mwachitsanzo, mawonekedwe ake okhudza-screen-screen amapereka deta yeniyeni yeniyeni yothandizira madokotala kuti adziwe zosankha zachipatala. Dongosololi limaperekanso mawu omveka otengera kutentha - kulola kuti adokotala aziganizira nthawi komanso chidwi kwa wodwalayo.
Vinclose idakhazikitsidwa mu 2014 kuti ipititse patsogolo chithandizo cha CVI kudzera muukadaulo wa radiofrequency ablation. Kuyambira pamenepo, kampaniyo yadzipereka kuti ipereke patsogolo luso laukadaulo komanso njira zogwirira ntchito kwa madotolo omwe amathandizira CVI, komanso kuthandizira kukulitsa kukhutitsidwa kwa odwala. Venclose ™ Dongosololi litha kugwiritsidwa ntchito m'mabungwe osiyanasiyana azachipatala ku United States ndi Europe. Zolinga zamalonda sizinaululidwe. Ntchitoyi ikuyembekezeka kukhala yocheperako pakuchita zachuma kwa BD mu fy2022.
Makumi biliyoni msika
Mu 2020, msika wapadziko lonse lapansi wa zida zamankhwala zapadziko lonse lapansi ukuyembekezeka kufika US $ 8.92 biliyoni (yofanana ndi RMB 56.8 biliyoni), ndipo United States ikadali msika waukulu kwambiri padziko lonse lapansi. Kulowererapo kwa venous ndi gawo lamsika wolowererapo, ndipo msika wapakhomo wa venous ukukula mwachangu. Mu 2013, kukula kwa msika wa zida zopangira ma venous ku China kunali 370million yuan. Mu 2017, kukula kwa msika wa kulowererapo kwa venous kwakwera mpaka RMB 890million. Kukula kofulumira kumeneku kudzakwera kwambiri ndi kukula kwa venous kulowa mu ntchito yachipatala. Pofika chaka cha 2022, msika udzafika pa RMB 3.1 biliyoni, ndikukula kwapachaka kwa 28.4%.
Malinga ndi ziwerengero, anthu 100000-300000 amamwalira ndi venous thrombosis chaka chilichonse ku United States, ndipo anthu 500000 amafa ndi venous thrombosis chaka chilichonse ku Europe. Mu 2019, chiwerengero cha odwala mitsempha ya varicose ku China chinafika 390million; Pali odwala 1.5 miliyoni omwe ali ndi vuto la venous thrombosis; Kuchuluka kwa kupsinjika kwa mitsempha ya iliac ndi 700000 ndipo akuyembekezeka kufika 2million pofika 2030.
Ndi kusonkhanitsa kwakukulu kwa ma coronary stents, cholinga cha kulowererapo kwa mitsempha chinasintha kuchokera ku mitsempha ya mitsempha kupita ku mitsempha ya mitsempha ndi zotumphukira. Kulowetsedwa kwapang'onopang'ono kumaphatikizapo kulowererapo kwa mitsempha yotumphukira komanso kulowererapo kwa venous. Kulowetsedwa kwa venous kunayamba mochedwa koma kudakula mwachangu. Malinga ndi kuwerengera kwachitetezo cha mafakitale, mtengo wamsika wa zida zaku China zopangira venous makamaka pochiza matenda wamba monga mitsempha ya varicose, venous thrombosis yakuya ndi iliac vein compression syndrome ndi pafupifupi 19.46 biliyoni.
Msika wozungulirawu, womwe upitilira 10 biliyoni wa yuan, wakopa zimphona zamitundu yosiyanasiyana monga BD, Medtronic ndi Boston sayansi. Alowa mumsika msanga, ali ndi mabizinesi akuluakulu ndipo apanga mzere wolemera wazinthu. Mabizinesi am'deralo nawonso akwera motsatira. Mabizinesi monga ukadaulo wa Xianjian ndi guichuang Tongqiao asunga mapaipi olemera a R & D m'munda wa mitsempha.
Njira yochotsera mitsempha yapakhomo
Ndi kuyimitsidwa kwa opaleshoni yocheperako kwambiri ya mitsempha ya varicose, chithandizo chocheperako chidzalowa m'malo mwa opaleshoni yachikale, ndipo kuchuluka kwa opaleshoni kumawonjezeka kwambiri. Pakati pa njira zochiritsira zochepa, radiofrequency ablation (RFA) ndi intracavitary laser ablation (EVLA) ndi njira ziwiri zotsimikiziridwa zochotseratu. RFA imapanga zoposa 70% ya intracavitary thermal ablation ku China mu 2019. Pakali pano, pali machitidwe awiri ovomerezeka a radiofrequency ablation ku China. Pali makamaka ma catheter atatu otumphukira a radiofrequency ablation omwe akugulitsidwa ku China, omwe amapangidwa ndi mabizinesi akunja, omwe ndi, kutseka mwachangu ndi kutseka ma RF a Medtronic ndi evrf intravenously radiofrequency closure system of F care systems NV.
Njira zatsopano zopangira ma radiofrequency ablation zimayang'ana kwambiri kuchepetsa zovuta. Zovuta zazikulu za mankhwala omwe alipo ndi ma radiofrequency ablation ndi kuyaka kwa khungu, kupatukana kwa mitsempha, subcutaneous ecchymosis ndi kutupa, komanso kuvulala kwa mitsempha ya saphenous. Kuwongolera mphamvu, jekeseni wa subcutaneous wamadzimadzi otupa ndi chithandizo chanthawi zonse cha kukakamiza kumatha kuchepetsa zovuta zomwe zimachitika. Kutentha kwa kutentha kumafuna anesthesia ya tumescent isanaperekedwe mphamvu, zomwe zingabweretse vuto kwa wodwala ndipo zingatalikitse nthawi yogwira ntchito.
Pachifukwa ichi, Medtronic yayang'ana kwambiri pa venaseal, chinthu chotseka kutentha kwanthawi zonse. Mfundo ya dongosolo lotsekerali ndikugwiritsa ntchito catheter kuti alowetse zomatira mumtsempha kuti akwaniritse zotsatira za kutseka kwa mitsempha. Venaseal idavomerezedwa ndi FDA kuti ilembetsedwe mu 2015. M'zaka zaposachedwa, yakhala malo okulirapo pabizinesi yozungulira ya Medtronic. Pakadali pano, mankhwalawa sanalembedwe ku China.
Pakalipano, mabizinesi apakhomo amayang'ana kwambiri kukhazikika kwa zinthu zamtundu wa radiofrequency ablation kwa varicose mitsempha ablation ndikuchepetsa zovuta zamafuta ablation; Dongosolo losinthika, losinthika komanso lanzeru la radiofrequency ablation lidzachepetsa kwambiri zovuta zogwirira ntchito, ndipo ndi gawo lofunikira pakuwongolera kwazinthu. Mabizinesi apakhomo a R & D opangira ma radiofrequency ablation akuphatikiza xianruida ndi guichuangtong mlatho. Kusakhutitsidwa kwa msika kumayendetsa mabizinesi ambiri kuti asonkhane panjira iyi, ndipo mpikisano wamtunduwu udzakhala wowopsa mtsogolo.
Kuchokera pakuwona kwa omwe akutenga nawo gawo m'nyumba, njira yopikisana pamsika yolowera m'mitsempha yapakhomo idawonekeranso. Omwe akutenga nawo mbali akuphatikiza mabizinesi amitundu yosiyanasiyana omwe akuimiridwa ndi Medtronic, Boston science ndi bidi zachipatala; Atsogoleri apakhomo oimiridwa ndi xianruida ndi Xinmai azachipatala, komanso angapo omwe akuyamba kumene.
Nthawi yotumiza: Jun-28-2022